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產(chǎn)品規(guī)格
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BN40346R-100ul
100ul
￥2360.00
交叉反應：Human,Mouse(predicted:Rat,Dog,Pig,Cow,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN40346R-200ul
200ul
￥3490.00
交叉反應：Human,Mouse(predicted:Rat,Dog,Pig,Cow,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
產(chǎn)品描述
| 英文名稱 | CLIC6 |
| 中文名稱 | 氯離子通道蛋白6抗體 |
| 別 名 | Chloride channel form A; Chloride intracellular channel 6; Chloride intracellular channel protein 6; CLIC1L; Clic6; CLIC6_HUMAN; Parchorin. |
| 研究領域 | 腫瘤 神經(jīng)生物學 通道蛋白 細胞膜受體 G蛋白偶聯(lián)受體 新陳代謝 G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Rabbit, Sheep, ) |
| 產(chǎn)品應用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 73kDa |
| 細胞定位 | 細胞漿 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CLIC6:531-630/704 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | CLIC6 (chloride intracellular channel 6) is believed to play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport. The CLIC6 gene is a rare example of large-scale segmental paralogy in which a large (approximately 500 kb) segment on human chromosome (HC) 21 (21q22) is triplicated on HC 1 and HC 6. CLIC6 is also known to interact with dopamine receptors DRD2, DRD3 and DRD4. CLIC6 is primarily expressed in the cytoplasm, however, upon chloride ion efflux from the cell, CLIC6 is translocated to the plasma membrane. CLIC6 has been identified in brain, placenta, pancreas and liver. Function: May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport. Subunit: Interacts with dopamine receptors DRD2, DRD3 and DRD4 Subcellular Location: Cytoplasm. Cell membrane. Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane. Tissue Specificity: Expressed in brain, placenta, pancreas and liver. Post-translational modifications: Phosphorylated. Similarity: Belongs to the chloride channel CLIC family. Contains 1 GST C-terminal domain. SWISS: Q96NY7 Gene ID: 54102 Database links: Entrez Gene: 54102 Human Omim: 615321 Human SwissProt: Q96NY7 Human Unigene: 473695 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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