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HS2ST1蛋白抗體

產(chǎn)品貨號(hào)：

BN40497R
中文名稱(chēng)：

HS2ST1蛋白抗體
英文名稱(chēng)：

Rabbit anti-HS2ST1 Polyclonal antibody
品牌：

Biorigin

貨號(hào)

產(chǎn)品規(guī)格

售價(jià)

備注
BN40497R-100ul

100ul

￥2360.00

交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40497R-200ul

200ul

￥3490.00

交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱(chēng)	HS2ST1
中文名稱(chēng)	HS2ST1蛋白抗體
別名	2-O-sulfotransferase; 2OST; dJ604K5.2; FLJ11317; heparan sulfate 2 O sulfotransferase 1; Heparan sulfate 2-O-sulfotransferase 1; HS2ST_HUMAN; hs2st1; KIAA0448; MGC131986.
研究領(lǐng)域	細(xì)胞生物信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白
抗體來(lái)源	Rabbit
克隆類(lèi)型	Polyclonal
交叉反應(yīng)	Human, Mouse, (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	42kDa
細(xì)胞定位	細(xì)胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human HS2ST1:221-320/356
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	Heparan sulfate structures, which are responsible for executing multiple biologic activities, are generated and regulated by heparan sulfate biosynthetic enzymes. HS2ST1 is a 356 amino acid single-pass type II membrane protein that localizes to the golgi apparatus and belongs to the sulfotransferase 3 family. Expressed as multiple alternatively spliced isoforms, HS2ST1 functions to catalyze the transfer of sulfate groups to hexuronic acid residues within maturing heparan sulfate (HS), an event which is crucial for proper HS-related ligand binding and signaling processes. HS2ST1 is subject to post-translational N-glycosylation and, in addition to its role in HS function, may be involved in proper kidney formation. Function: Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues. Subcellular Location: Golgi apparatus membrane. Post-translational modifications: N-glycosylated. Similarity: Belongs to the sulfotransferase 3 family. SWISS: Q7LGA3 Gene ID: 9653 Database links: Entrez Gene: 9653 Human Entrez Gene: 23908 Mouse Entrez Gene: 292155 Rat GenBank: AA987571.1 Human SwissProt: Q7LGA3 Human SwissProt: Q8R3H7 Mouse Unigene: 137733 Human Unigene: 726055 Human Unigene: 12863 Mouse Unigene: 465667 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.