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富含亮氨酸重復(fù)蛋白51抗體
  • 產(chǎn)品貨號：
    BN40518R
  • 中文名稱：
    富含亮氨酸重復(fù)蛋白51抗體
  • 英文名稱：
    Rabbit anti-LRTOMT/LRRC51 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40518R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat,Dog 推薦應(yīng)用：WB,ELISA

  • BN40518R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat,Dog 推薦應(yīng)用：WB,ELISA

產(chǎn)品描述

英文名稱LRTOMT/LRRC51
中文名稱富含亮氨酸重復(fù)蛋白51抗體
別    名COMT2; DFNB63; Leucine rich repeat-containing protein 51; Leucine rich transmembrane and 0-methyltransferase domain containing; LRRC51; LRTOMT1; LRTOMT2; Protein LRTOMT1.  
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)(predicted: Mouse, Rat, hu, mo, rat, dog)
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量22kDa
細(xì)胞定位細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human LRTOMT/LRRC51:1-100/192 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene. [provided by RefSeq, Sep 2012]

Subcellular Location:
Cytoplasmic

Similarity:
Contains 3 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.

SWISS:
Q96E66

Gene ID:
220074

Database links:

Entrez Gene: 220074 Human

Entrez Gene: 69358 Mouse

Omim: 612414 Human

SwissProt: Q96E66 Human

SwissProt: Q9DAK8 Mouse

SwissProt: B6CZ61 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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