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G2期/S期應(yīng)答相關(guān)蛋白1抗體
  • 產(chǎn)品貨號(hào)：
    BN40823R
  • 中文名稱：
    G2期/S期應(yīng)答相關(guān)蛋白1抗體
  • 英文名稱：
    Rabbit anti-GTSE-1 Polyclonal antibody
  • 品牌：
    Biorigin

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    產(chǎn)品規(guī)格

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  • BN40823R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Pig,Cow) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN40823R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Pig,Cow) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱GTSE-1
中文名稱G2期/S期應(yīng)答相關(guān)蛋白1抗體
別    名G2 and S phase-expressed protein 1; B99; B99 homolog; G 2 and S phase expressed 1; G two S phase expressed protein 1; GTSE 1; GTSE-1; GTSE1; GTSE1_HUMAN.  
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  細(xì)胞周期蛋白  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Chicken, Pig, Cow, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量77kDa
細(xì)胞定位細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GTSE-1:651-739/739 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]

Function:
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.

Subcellular Location:
Cytoplasm, cytoskeleton. Note=Associated with microtubules.

Post-translational modifications:
Phosphorylated in mitosis.

Similarity:
Sequence=CAQ09324.2; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAQ10552.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.

SWISS:
Q9NYZ3

Gene ID:
51512

Database links:

Entrez Gene: 51512 Human

Omim: 607477 Human

SwissProt: Q9NYZ3 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.