欧美日韩国产一区高清_亚洲综合日韩免费av_在线黄色视频不卡_美女高潮喷水免费网站_亚洲AV日韩AV蜜桃在线播放_色99久久综合网_干人妻潮喷无码视频_天天看片高清观看免费_国模性爱无码视频_在线亚洲精品国产二区图片欧美

最近搜索：細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
首頁>>免疫學(xué)>>一抗>>腺苷酸環(huán)化酶1抗體
腺苷酸環(huán)化酶1抗體
  • 產(chǎn)品貨號：
    BN40943R
  • 中文名稱：
    腺苷酸環(huán)化酶1抗體
  • 英文名稱：
    Rabbit anti-Adenylate cyclase 1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40943R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Rat(predicted:Mouse) 推薦應(yīng)用：WB,IHC-P,ELISA

  • BN40943R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Rat(predicted:Mouse) 推薦應(yīng)用：WB,IHC-P,ELISA

產(chǎn)品描述

英文名稱Adenylate cyclase 1
中文名稱腺苷酸環(huán)化酶1抗體
別    名3'5' cyclic AMP synthetase; ADCY1; adenyl cyclase; adenylate cyclase type I; ATP pyrophosphate lyase; Brain adenylate cyclase 1; Ca(2+)/calmodulin activated adenylyl cyclase; EC 4.6.1.1; ADCY1_HUMAN; Adenylate cyclase type 1; ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase. .  
研究領(lǐng)域腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Rat,  (predicted: Mouse, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量123kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human adenylate cyclase type I:751-850/1119 <Cytoplasmic>
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The membrane bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein coupled receptors. Eight human AC isoforms (AC-1 through AC-4) have been identified up to now and genes for at least nine adenylate cyclase (AC-1-AC-9) have been cloned characterized and sequenced. This is a calmodulin-sensitive adenylyl cyclase which may be involved in regulatory processes in the central nervous system. It may play a role in neuronal plasticity, memory acquisition and learning and is expressed predominantly in the brain, retina and adrenal medulla.

Function:
This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Brain, retina and adrenal medulla.

Similarity:
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains.

SWISS:
Q08828

Gene ID:
107

Database links:

Entrez Gene: 107 Human

Entrez Gene: 432530 Mouse

Omim: 103072 Human

SwissProt: Q08828 Human

SwissProt: O88444 Mouse

Unigene: 192215 Human

Unigene: 259733 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

腺苷酸環(huán)化酶(adenylate cyclase, AC) 是G蛋白偶聯(lián)受體家族之一，是膜整合蛋白,它的氨基端和羧基端都朝向細(xì)胞質(zhì)。AC在膜的細(xì)胞質(zhì)面有兩個催化結(jié)構(gòu)域,還有兩個膜整合區(qū),每個膜整合區(qū)分別有6個跨膜的α螺旋。哺乳動物中已發(fā)現(xiàn)6個腺苷酸環(huán)化酶異構(gòu)體。由于AC能夠?qū)TP轉(zhuǎn)變成cAMP,引起細(xì)胞的信號應(yīng)答,因此,腺苷酸環(huán)化酶是G蛋白偶聯(lián)系統(tǒng)中的效應(yīng)