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嗜中性粒細(xì)胞胞漿因子1抗體

產(chǎn)品貨號(hào)：

BN40976R
中文名稱：

嗜中性粒細(xì)胞胞漿因子1抗體
英文名稱：

Rabbit anti-NCF1 Polyclonal antibody
品牌：

Biorigin

貨號(hào)

產(chǎn)品規(guī)格

售價(jià)

備注
BN40976R-100ul

100ul

￥2360.00

交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog) 推薦應(yīng)用：WB,Flow-Cyt,ELISA
BN40976R-200ul

200ul

￥3490.00

交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog) 推薦應(yīng)用：WB,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱	NCF1
中文名稱	嗜中性粒細(xì)胞胞漿因子1抗體
別名	47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NCF 47K; NCF-1; NCF-47K; Ncf1; NCF1_HUMAN; Neutrophil cytosol factor 1; Neutrophil cytosolic factor 1; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox organizing protein 2; Nox-organizing protein 2; NOXO2; p47 phox; p47-phox; SH3 and PX domain containing protein 1A; SH3 and PX domain-containing protein 1A; SH3PXD1A.

研究領(lǐng)域	腫瘤細(xì)胞生物免疫學(xué) 新陳代謝
抗體來(lái)源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, (predicted: Rat, Dog, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1ug/test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	45kDa
細(xì)胞定位	細(xì)胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human NCF1:151-250/390
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	NCF1, along with NCF2 and a membrane bound cytochrome b558, is required for activation of the latent NADPH oxidase necessary for superoxide production. Defects in NCF1 are the cause of autosomal cytochrome-b-positive chronic granulomatous disease type 1 (CGD). Function: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Subunit: Interacts with NOXA1. Interacts with ADAM15. Interacts with TRAF4. Interacts with FASLG. Subcellular Location: Cytoplasm. Post-translational modifications: Phosphorylated by PRKCD; phosphorylation induces activation of NCF1 and NADPH oxidase activity. DISEASE: Granulomatous disease, chronic, cytochrome-b-positive 1, autosomal recessive (CGD1) [MIM:233700]: A disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Contains 1 PX (phox homology) domain. Contains 2 SH3 domains. SWISS: P14598 Gene ID: 653361 Database links: Entrez Gene: 281345 Cow Entrez Gene: 653361 Human Entrez Gene: 17969 Mouse Entrez Gene: 100134857 Pig Entrez Gene: 100008803 Rabbit Entrez Gene: 114553 Rat Omim: 608512 Human SwissProt: O77774 Cow SwissProt: P14598 Human SwissProt: Q09014 Mouse Unigene: 647047 Human Unigene: 655201 Human Unigene: 425296 Mouse Unigene: 38575 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.