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產(chǎn)品規(guī)格
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BN41138R-100ul
100ul
¥2360.00
交叉反應(yīng):Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN41138R-200ul
200ul
¥3490.00
交叉反應(yīng):Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
產(chǎn)品描述
英文名稱 | TRAK1 |
中文名稱 | 驅(qū)動蛋白結(jié)合蛋白1抗體 |
別 名 | 106 kDa O-GlcNAc transferase-interacting protein; 106 kDa O GlcNAc transferase interacting protein; KIAA1042; OGT(O Glc NAc transferase) interacting protein 106 KDa; OIP106; TRAK1_HUMAN; Trafficking kinesin binding protein 1; Trafficking kinesin-binding protein 1; Trafficking protein kinesin binding 1; TRAK 1. |
研究領(lǐng)域 | 腫瘤 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞骨架 腫瘤細(xì)胞生物標(biāo)志物 線粒體 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Mouse, (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, ) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 106kDa |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 線粒體 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TRAK1:171-270/953 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
產(chǎn)品介紹 | The specific function of TRAK1 remains unknown. It interacts with O-GlcNAc transferase, RHOT1/Miro-1 and RHOT2/Miro-2. It shows high expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Function: Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors. Subunit: Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2. Interacts with HGS. Interacts with GABRA1. Interacts with KIF5C. Subcellular Location: Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome. Tissue Specificity: High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined. Post-translational modifications: O-glycosylated. Similarity: Contains 1 HAP1 N-terminal domain. SWISS: Q9UPV9 Gene ID: 22906 Database links: Entrez Gene: 22906 Human Omim: 608112 Human SwissProt: Q9UPV9 Human Unigene: 535711 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |