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產(chǎn)品規(guī)格
售價
備注
BN41233R-100ul
100ul
¥2360.00
交叉反應:Mouse(predicted:Human,Rat,Dog,Pig,Cow,Sheep) 推薦應用:Flow-Cyt,ELISA
BN41233R-200ul
200ul
¥3490.00
交叉反應:Mouse(predicted:Human,Rat,Dog,Pig,Cow,Sheep) 推薦應用:Flow-Cyt,ELISA
產(chǎn)品描述
英文名稱 | ERN2 |
中文名稱 | 內(nèi)質(zhì)網(wǎng)核信號轉(zhuǎn)導蛋白2抗體 |
別 名 | IRE1b; Endoplasmic reticulum to nucleus signaling 2; ER to nucleus signalling 2; ERN 2; Ern1; hIRE2p; Inositol requiring 1 beta; Inositol requiring protein 2; Ire1; Ire1 beta; IRE1 S. cerevisiae homolog of; IRE2; Serine/threonine protein kinase/endoribonuclease IRE2; ERN2_HUMAN. |
研究領(lǐng)域 | 細胞生物 信號轉(zhuǎn)導 細胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 激酶和磷酸酶 表觀遺傳學 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Sheep, ) |
產(chǎn)品應用 | ELISA=1:5000-10000 Flow-Cyt=2ug/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 98kDa |
細胞定位 | 細胞漿 細胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ERN2:465-550/926 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
產(chǎn)品介紹 | ERN2, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. It is pro-apoptotic and appears to play no role in the unfolded-protein response, unlike closely related proteins. Function: Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Post-translational modifications: Autophosphorylated. Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 KEN domain. Contains 1 protein kinase domain. SWISS: O75460 Gene ID: 10595 Database links: Entrez Gene: 10595 Human Entrez Gene: 26918 Mouse Omim: 604034 Human SwissProt: O75460 Human SwissProt: Q9EQY0 Mouse Unigene: 133982 Human Unigene: 20452 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |