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肌萎縮相關(guān)蛋白1抗體
  • 產(chǎn)品貨號(hào)：
    BN41245R
  • 中文名稱：
    肌萎縮相關(guān)蛋白1抗體
  • 英文名稱：
    Rabbit anti-RERE Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41245R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse) 推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA

  • BN41245R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse) 推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱RERE
中文名稱肌萎縮相關(guān)蛋白1抗體
別    名ARG; arginine glutamic acid dipeptide (RE) repeats; arginine glutamic acid dipeptide repeats; Arginine glutamic acid dipeptide repeats protein; Arginine-glutamic acid dipeptide repeats protein; ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE; ARP; ATN1L; Atr2; atrophin 1 like; Atrophin 1 like protein; Atrophin 1 related protein; atrophin 2; atrophin related protein; ATROPHIN-1-ASSOCIATED PROTEIN; Atrophin-1-like protein; Atrophin-1-related protein; atrophin-2; ATROPHIN-RELATED PROTEIN; DNB1; Rere; RERE_HUMAN.  
研究領(lǐng)域細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Chicken, Dog, Cow, Horse, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量172kDa
細(xì)胞定位細(xì)胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human RERE:521-620/1566 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹FunctionPlays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.

Function:
Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.

Subunit:
Interacts with HDAC1 (By similarity). Interacts with ATN1. Interaction with ATN1 is improved when the poly-Gln region of ATN1 is extended. Interacts with FAT1.

Subcellular Location:
Nucleus. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.

Tissue Specificity:
Widely expressed. Expressed in tumor cell lines.

DISEASE:
Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line NGP. Translocation t(1;15)(p36.2;q24).

Similarity:
Contains 1 BAH domain.
Contains 1 ELM2 domain.
Contains 1 GATA-type zinc finger.
Contains 1 SANT domain.

SWISS:
Q9P2R6

Gene ID:
473

Database links:
UniProtKB/Swiss-Prot: Q9P2R6.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















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