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絲氨酸/蘇氨酸蛋白激酶3抗體

產(chǎn)品貨號：

BN41259R
中文名稱：

絲氨酸/蘇氨酸蛋白激酶3抗體
英文名稱：

Rabbit anti-MST3/STK3 Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價(jià)

備注
BN41259R-100ul

100ul

￥2360.00

交叉反應(yīng)：Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Dog,Chicken) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
BN41259R-200ul

200ul

￥3490.00

交叉反應(yīng)：Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Dog,Chicken) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱	MST3/STK3
中文名稱	絲氨酸/蘇氨酸蛋白激酶3抗體
別名	Kinase responsive to stress 1; KRS1; Mammalian STE20 like protein kinase 2; Mammalian sterile 20-like 2; Mess1; MST; MST-2; MST2; Mst3; Serine/threonine kinase 3 (STE20 homolog, yeast); Serine/threonine kinase 3 (Ste20, yeast homolog); Serine/threonine protein kinase 3; Serine/threonine protein kinase Krs1; STE20 like kinase MST2.

研究領(lǐng)域	細(xì)胞生物信號轉(zhuǎn)導(dǎo) 細(xì)胞凋亡轉(zhuǎn)錄調(diào)節(jié)因子激酶和磷酸酶
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Mouse, (predicted: Human, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	56kDa
細(xì)胞定位	細(xì)胞核細(xì)胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human STK3:101-200/491
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	STK3 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Subunit: Homodimer; mediated via the coiled-coil region. Interacts with NORE1, which inhibits autoactivation. Interacts with and stabilizes SAV1. Interacts with RAF1, which prevents dimerization and phosphorylation. Interacts with RASSF1. Interacts (via SARAH domain) with isoform 1 of NEK2. Interacts with ESR1 only in the presence of SAV1. Interacts with PKB/AKT1. Forms a tripartite complex with MOBKL1B and STK38. Interacts with RASSF2 (via SARAH domain). Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Expressed at high levels in adult kidney, skeletal and placenta tissues and at very low levels in adult heart, lung and brain tissues. Similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. Contains 1 protein kinase domain. Contains 1 SARAH domain. SWISS: Q9Y6E0 Gene ID: 8428 Database links: Entrez Gene: 8428 Human Entrez Gene: 223255 Mouse Entrez Gene: 361092 Rat Omim: 604984 Human SwissProt: Q9Y6E0 Human SwissProt: Q99KH8 Mouse SwissProt: B0LT89 Rat Unigene: 508514 Human Unigene: 390756 Mouse Unigene: 442081 Mouse Unigene: 472866 Mouse Unigene: 105397 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.