欧美日韩国产一区高清_亚洲综合日韩免费av_在线黄色视频不卡_美女高潮喷水免费网站_亚洲AV日韩AV蜜桃在线播放_色99久久综合网_干人妻潮喷无码视频_天天看片高清观看免费_国模性爱无码视频_在线亚洲精品国产二区图片欧美

最近搜索：細胞培養(yǎng) 微生物學 分子生物 生物化學
首頁>>免疫學>>一抗>>細胞核分離基因C蛋白抗體
細胞核分離基因C蛋白抗體
  • 產品貨號：
    BN41277R
  • 中文名稱：
    細胞核分離基因C蛋白抗體
  • 英文名稱：
    Rabbit anti-NUDC Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產品規(guī)格

    售價

    備注

  • BN41277R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

  • BN41277R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

產品描述

英文名稱NUDC
中文名稱細胞核分離基因C蛋白抗體
別    名HNUDC; MNUDC; MNUDC protein; NPD011; Nuclear distribution gene C (A.nidulans) homolog; Nuclear distribution gene C homolog; Nuclear distribution gene C homolog (A. nidulans); Nuclear distribution protein C homolog; Nuclear migration protein nudC; nudC; NUDC_HUMAN; OTTHUMP00000004405; SIG 92; SIG92.  
研究領域腫瘤  細胞生物  神經生物學  細胞周期蛋白  細胞分化  表觀遺傳學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, Rabbit, )
產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量36kDa
細胞定位細胞核 細胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human NUDC:271-331/331 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產品介紹This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012].

Function:
Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.

Subunit:
Binds PLK1. Binds PAFAH1B1 (By similarity). Part of a complex containing PLK1, NUDC, dynein and dynactin.

Subcellular Location:
Cytoplasm, cytoskeleton. Nucleus. Note=In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern.

Tissue Specificity:
Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.

Post-translational modifications:
Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases.

Similarity:
Belongs to the nudC family.
Contains 1 CS domain.

SWISS:
Q9Y266

Gene ID:
10726

Database links:
NCBI Reference Sequence: NP_006591.1
UniProtKB/Swiss-Prot: Q9Y266.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

















image.png

image.png