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膠質(zhì)源性連接蛋白抗體

產(chǎn)品貨號(hào)：

BN41411R
中文名稱：

膠質(zhì)源性連接蛋白抗體
英文名稱：

Rabbit anti-GDN Polyclonal antibody
品牌：

Biorigin

貨號(hào)

產(chǎn)品規(guī)格

售價(jià)

備注
BN41411R-100ul

100ul

￥2360.00

交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
BN41411R-200ul

200ul

￥3490.00

交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱	GDN
中文名稱	膠質(zhì)源性連接蛋白抗體
別名	Glia derived nexin; Protease inhibitor 7; GDN; GDN_HUMAN; Glia-derived nexin; P17 antibody Peptidase inhibitor 7; Pi-7; Plasminogen activator inhibitor type 1, member 2; PN-1; PN1; PNI; Protease nexin 1; Protease nexin I; Serpin E2; Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; SERPINE 2; Serpine2.
研究領(lǐng)域	細(xì)胞生物神經(jīng)生物學(xué)
抗體來(lái)源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, Rat, (predicted: Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	42kDa
細(xì)胞定位	細(xì)胞外基質(zhì) 分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human GDN/SERPINE2:301-398/398
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	The serine protease inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Protease nexin-1 (PN-1) is a serpin that inactivates several proteases, including thrombin, urokinase, plasminogen activators (PA) and plasmin. It is involved in tissue remodeling, cellular invasiveness, matrix degradation and tumor growth. PN-1 expression is abundant in the nervous system, where it inhibits thrombin, thereby playing a role in neural injury and repair processes. An imbalance between PN-1 and thrombin may be a contributing factor in the pathology of Alzheimer’s disease. Function: Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin. Subcellular Location: Secreted, extracellular space. Similarity: Belongs to the serpin family. SWISS: P07093 Gene ID: 5270 Database links: Entrez Gene: 5270 Human Entrez Gene: 20720 Mouse Entrez Gene: 29366 Rat Omim: 177010 Human SwissProt: P07093 Human SwissProt: Q07235 Mouse SwissProt: P07092 Rat Unigene: 38449 Human Unigene: 708453 Human Unigene: 3093 Mouse Unigene: 2271 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.