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緊密連接蛋白抗體

產(chǎn)品貨號：

BN41606R
中文名稱：

緊密連接蛋白抗體
英文名稱：

Rabbit anti-Occludin Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價

備注
BN41606R-50ul

50ul

￥1486.00

交叉反應(yīng)：Rat,Mouse,Human(predicted:Sheep,Cow,Pig,Dog) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN41606R-100ul

100ul

￥2360.00

交叉反應(yīng)：Rat,Mouse,Human(predicted:Sheep,Cow,Pig,Dog) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN41606R-200ul

200ul

￥3490.00

交叉反應(yīng)：Rat,Mouse,Human(predicted:Sheep,Cow,Pig,Dog) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱	Occludin
中文名稱	緊密連接蛋白抗體
別名	Occludin, Occludin-1; Occludin1; Occludin 1; FLJ08163; BLCPMG; FLJ18079; FLJ77961; FLJ94056; MGC34277; Occludin; OCLN; OCLN_HUMAN; Tight junction protein occludin.

抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, Rat, (predicted: Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	59kDa
細(xì)胞定位	細(xì)胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Occludin:151-250/522 <Extracellular>
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described. [provided by RefSeq]. Function: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Subunit: Interacts with TJP1/ZO1 and with VAPA. Subcellular Location: Membrane; Multi-pass membrane protein. Cell junction, tight junction. Tissue Specificity: Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Dephosphorylated by PTPRJ. May be phosphorylated by PKC during translocation to cell-cell contacts. Similarity: Belongs to the ELL/occludin family. Contains 1 MARVEL domain. SWISS: Q16625 Gene ID: 100506658 Database links: Entrez Gene: 18260 Mouse Entrez Gene: 100506658 Human Entrez Gene: 397236 Pig Entrez Gene: 83497 Rat Entrez Gene: 403844 Dog Omim: 602876 Human SwissProt: Q28269 Dog SwissProt: Q16625 Human SwissProt: Q61146 Mouse SwissProt: Q6P6T5 Rat Unigene: 592605 Human Unigene: 4807 Mouse Unigene: 31429 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.