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首頁>>免疫學(xué)>>一抗>>5-羥色胺受體4抗體

5-羥色胺受體4抗體

產(chǎn)品貨號：

BN41781R
中文名稱：

5-羥色胺受體4抗體
英文名稱：

Rabbit anti-5HT4 Receptor Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價

備注
BN41781R-50ul

50ul

￥1486.00

交叉反應(yīng)：Human,Mouse,Rat(predicted:Chicken,Cow) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41781R-100ul

100ul

￥2360.00

交叉反應(yīng)：Human,Mouse,Rat(predicted:Chicken,Cow) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41781R-200ul

200ul

￥3490.00

交叉反應(yīng)：Human,Mouse,Rat(predicted:Chicken,Cow) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱	5HT4 Receptor
中文名稱	5-羥色胺受體4抗體
別名	5-HTR4 (5-hydroxytryptamine (serotonin) receptor 4a); Htr4a; 5-HT4; 5-HT4A; 5HT4; Htr45 HT 4; 5 HT4; 5 HT4R; 5 hydroxytryptamine 4 receptor; 5 hydroxytryptamine receptor 4; 5 hydroxytryptamine serotonin receptor 4; 5 hydroxytryptamine4 receptor; 5HT4; 5HT4R; Cardiac 5 HT4 receptor; HTR 4; HTR4; Serotonin 5 HT4 receptor; Serotonin receptor 4; 5HT4R_HUMAN.

研究領(lǐng)域	神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 通道蛋白細(xì)胞膜受體轉(zhuǎn)運蛋白
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Mouse, Rat, (predicted: Human, Chicken, Cow, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:200-800 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	43kDa
細(xì)胞定位	細(xì)胞漿細(xì)胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human 5-HTR4:21-120/388
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010] Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Subunit: Isoform 5-HT4(A) interacts with MAGI2, MPP3, SLC9A3R1 and SNX27 isoforms 1 and 2. Isoform 5-HT4(E) interacts with INADL, NOS1 and SEC23A. Isoform 5-HT4(A) forms a complex including SLC9A3R1 and EZR. Subcellular Location: Cell membrane; Multi-pass membrane protein. Endosome. Note=Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. Tissue Specificity: soform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q13639 Gene ID: 3360 Database links: Entrez Gene: 3360 Human Entrez Gene: 15562 Mouse Entrez Gene: 25324 Rat GenBank: NP_000861.1 Human Omim: 602164 Human SwissProt: O70528 Guinea pig SwissProt: Q13639 Human SwissProt: P97288 Mouse SwissProt: Q29006 Pig SwissProt: Q62758 Rat Unigene: 483773 Human Unigene: 20440 Mouse Unigene: 10094 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.