欧美日韩国产一区高清_亚洲综合日韩免费av_在线黄色视频不卡_美女高潮喷水免费网站_亚洲AV日韩AV蜜桃在线播放_色99久久综合网_干人妻潮喷无码视频_天天看片高清观看免费_国模性爱无码视频_在线亚洲精品国产二区图片欧美

最近搜索：細(xì)胞培養(yǎng) 微生物學(xué) 分子生物生物化學(xué)

首頁(yè)>>免疫學(xué)>>一抗>>Ki67蛋白抗體

Ki67蛋白抗體

產(chǎn)品貨號(hào)：

BN41782R
中文名稱：

Ki67蛋白抗體
英文名稱：

Rabbit anti-Ki-67 Polyclonal antibody
品牌：

Biorigin

貨號(hào)

產(chǎn)品規(guī)格

售價(jià)

備注
BN41782R-50ul

50ul

￥1486.00

交叉反應(yīng)：Human,Mouse,Rat 推薦應(yīng)用：IHC-P,IF,ELISA
BN41782R-100ul

100ul

￥2360.00

交叉反應(yīng)：Human,Mouse,Rat 推薦應(yīng)用：IHC-P,IF,ELISA

產(chǎn)品描述

英文名稱	Ki-67
中文名稱	Ki67蛋白抗體
別名	Antigen identified by monoclonal antibody Ki 67; Antigen KI67; KIA; Ki-67; Ki67; MKI67; Proliferation related Ki 67 antigen; Antigen KI-67; KI67_HUMAN.

研究領(lǐng)域	腫瘤細(xì)胞生物信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來(lái)源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, Rabbit, (predicted: Rat, )
產(chǎn)品應(yīng)用	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	358kDa
細(xì)胞定位	細(xì)胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Ki67:1201-1300/3256
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation. Function: Thought to be required for maintaining cell proliferation. Subcellular Location: Nucleus. Chromosome. Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes. Similarity: Contains 1 FHA domain. SWISS: P46013 Gene ID: 4288 Database links: Entrez Gene: 4288 Human Entrez Gene: 17345 Mouse Entrez Gene: 246042 Rat Omim: 176741 Human SwissProt: P46013 Human SwissProt: Q91VE6 Mouse SwissProt: Q5RJM0 Rat Unigene: 689823 Human Unigene: 80976 Human Unigene: 4078 Mouse Unigene: 233802 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 細(xì)胞增殖標(biāo)志物(Proliferation Marker) Ki67與PCNA一樣，為細(xì)胞增殖的一種標(biāo)記，在細(xì)胞凋亡中S、G2 、M期均有表達(dá)，G0期缺如。 Ki-67增殖指數(shù)高低與許多腫瘤的分化程度、浸潤(rùn)、轉(zhuǎn)移以及預(yù)后密切相關(guān)，因此被廣泛作為各種惡性腫瘤的必檢項(xiàng)目之一。