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血管緊張素II受體樣蛋白1抗體
  • 產(chǎn)品貨號(hào)：
    BN41783R
  • 中文名稱(chēng)：
    血管緊張素II受體樣蛋白1抗體
  • 英文名稱(chēng)：
    Rabbit anti-Apelin Receptor Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41783R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN41783R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN41783R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱(chēng)Apelin Receptor
中文名稱(chēng)血管緊張素II受體樣蛋白1抗體
別    名APJ receptor; AGTR L1; AGTRL 1; AGTRL1; Angiotensin II receptor like 1; Angiotensin receptor like 1; Apelin receptor; APJ; B78; FLJ90771; G protein coupled receptor APJ; GPCR34; HG 11; HG11; MGC45246; MSR; msr/apj; Aplnr; Agtrl1; APLNR; FLJ96609; APJ_HUMAN.  
研究領(lǐng)域心血管  細(xì)胞生物  免疫學(xué)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源Rabbit
克隆類(lèi)型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Chicken, Dog, Horse, Rabbit, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量42kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Apelin Receptor :181-280/380 <Cytoplasmic>
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq

Function:
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P35414

Gene ID:
187

Database links:

Entrez Gene: 429337 Chicken

Entrez Gene: 615435 Cow

Entrez Gene: 187 Human

Entrez Gene: 23796 Mouse

Entrez Gene: 83518 Rat

Omim: 600052 Human

SwissProt: P35414 Human

SwissProt: Q9WV08 Mouse

SwissProt: Q9JHG3 Rat

Unigene: 438311 Human

Unigene: 29368 Mouse

Unigene: 7965 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications