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產(chǎn)品規(guī)格
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BN41925R-50ul
50ul
¥1486.00
交叉反應(yīng):Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat,Mouse) 推薦應(yīng)用:WB,Flow-Cyt,ELISA
BN41925R-100ul
100ul
¥2360.00
交叉反應(yīng):Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat,Mouse) 推薦應(yīng)用:WB,Flow-Cyt,ELISA
BN41925R-200ul
200ul
¥3490.00
交叉反應(yīng):Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat,Mouse) 推薦應(yīng)用:WB,Flow-Cyt,ELISA
產(chǎn)品描述
英文名稱 | Lactoferrin |
中文名稱 | 乳鐵蛋白抗體 |
別 名 | CKRX; GIG12; Growth inhibiting protein 12; HLF2; Homo sapiens chemokine receptor X; Kaliocin 1; Lactoferrin; Lactoferroxin A; Lactoferroxin B; Lactoferroxin C; Lactoferroxin-C; Lactotransferrin; LF; LTF; Neutrophil lactoferrin; Talalactoferrin alfa; Talalactoferrin; TRFL_HUMAN. |
研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 免疫學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) |
產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=0.2ug/test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 76kDa |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Lactoferrin:611-710/710 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
產(chǎn)品介紹 | Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Function: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Isoform DeltaLf: transcription factor with antiproliferative properties and inducing cell cycle arrest. Binds to DeltaLf response element found in the SKP1, BAX, DCPS, and SELH promoters. Subunit: Monomer. Found in a complex with LTF, CLU, EPPIN and SEMG1. Subcellular Location: Isoform 1: Secreted. Isoform DeltaLf: Cytoplasm. Nucleus. Post-translational modifications: Isoform DeltaLf: Ubiquitinated at Lys-379 and Lys-391. Similarity: Belongs to the transferrin family. Contains 2 transferrin-like domains. SWISS: P02788 Gene ID: 4057 Database links: Entrez Gene: 4057 Human Entrez Gene: 17002 Mouse Omim: 150210 Human SwissProt: P02788 Human SwissProt: P08071 Mouse Unigene: 529517 Human Unigene: 282359 Mouse Unigene: 218647 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |